2DSR

Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005520	molecular_function	insulin-like growth factor binding
B	0005576	cellular_component	extracellular region
G	0005520	molecular_function	insulin-like growth factor binding
G	0005576	cellular_component	extracellular region
I	0005179	molecular_function	hormone activity
I	0005576	cellular_component	extracellular region
I	0005615	cellular_component	extracellular space
I	0008083	molecular_function	growth factor activity

Functional Information from PROSITE/UniProt

site_id	PS00222
Number of Residues	16
Details	IGFBP_N_1 Insulin-like growth factor-binding protein (IGFBP) N-terminal domain signature. GCGCCatCAlglgmpC

Chain	Residue	Details
B	GLY31-CYS46

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site_id	PS00262
Number of Residues	15
Details	INSULIN Insulin family signature. CCFRsCDlrrLemyC

Chain	Residue	Details
I	CYS47-CYS61

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site_id	PS00484
Number of Residues	35
Details	THYROGLOBULIN_1_1 Thyroglobulin type-1 repeat signature. PipnCdrn.GnFhpkQchpaldgqrgkcWCVdrktG

Chain	Residue	Details
G	PRO179-GLY213

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