2DRZ
Crystal structure of the earthworm lectin C-terminal domain mutant in complex with lactose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 29-kDa galactose-binding lectin | polymer | 130 | 14432.2 | 2 | UniProt (O96048) Pfam (PF00652) | Lumbricus terrestris (common earthworm) | |
| 2 | C, D (C, D) | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 2 | In PDB BIRD (PRD_900004) GlyTouCan (G84224TW) | beta-lactose | ||
| 3 | E, F, G, H (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A, B: 131 - 260 (UniProt: O96048)
| PDB | External Database | Details |
|---|---|---|
| Gly 148 | Glu 148 | engineered mutation |
| Asn 227 | Ile 227 | engineered mutation |
| Gly 230 | Asp 230 | engineered mutation |
| Val 231 | Ile 231 | engineered mutation |
| Gly 237 | Glu 237 | engineered mutation |
| Ser 239 | Gly 239 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28864.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 684.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 384.3 | |
| All* | Total formula weight | 29933.2 |
