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2DR6

Crystal structure of a multidrug transporter reveal a functionally rotating mechanism

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
ACRBpolymer1053114217.73UniProt (P31224)
Pfam (PF00873)
Escherichia colimultidrug efflux transporter, Acriflavine resistance protein B
2D
(A)
DOXORUBICINnon-polymer543.51Chemie (DM2)
Sequence modifications
A, B, C: 1 - 1049 (UniProt: P31224)
PDBExternal DatabaseDetails
His 1050-expression tag
His 1051-expression tag
His 1052-expression tag
His 1053-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight342653.2
Non-Polymers*Number of molecules1
Total formula weight543.5
All*Total formula weight343196.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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