2DR6
Crystal structure of a multidrug transporter reveal a functionally rotating mechanism
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | ACRB | polymer | 1053 | 114217.7 | 3 | UniProt (P31224) Pfam (PF00873) | Escherichia coli | multidrug efflux transporter, Acriflavine resistance protein B |
| 2 | D (A) | DOXORUBICIN | non-polymer | 543.5 | 1 | Chemie (DM2) PubChem (1691) PubChem (32875) PubChem (41867) PubChem (83979) PubChem (23637978) PubChem (151537) PubChem (153517) PubChem (71199382) PubChem (17572077) PubChem (24871487) PubChem (44119991) PubChem (44307587) PubChem (44784745) PubChem (44286103) PubChem (51340272) PubChem (45039140) PubChem (45039115) PubChem (53298795) PubChem (53298798) PubChem (53487962) PubChem (56841075) PubChem (57156654) PubChem (3085300) PubChem (3246521) PubChem (57654443) PubChem (57676190) PubChem (57684283) PubChem (58166317) PubChem (58641042) PubChem (58918741) PubChem (59360012) PubChem (59392534) PubChem (66509033) PubChem (66687678) PubChem (58599010) PubChem (58648994) PubChem (67476623) PubChem (71113872) PubChem (68031993) PubChem (68652619) PubChem (69505664) PubChem (66728492) PubChem (70791143) PubChem (68247330) PubChem (5706446) PubChem (31703) PubChem (6604382) PubChem (6711224) PubChem (6713707) PubChem (89728269) PubChem (89728271) PubChem (89802959) PubChem (89848182) PubChem (89955946) PubChem (89970500) PubChem (91091768) PubChem (92209262) PubChem (92209263) PubChem (92402748) PubChem (11295712) PubChem (92849511) PubChem (92849512) PubChem (3246615) PubChem (155908452) PubChem (15558386) PubChem (15558389) PubChem (15558390) PubChem (15558391) PubChem (15558395) PubChem (15558402) PubChem (15558405) PubChem (15558406) PubChem (92249481) PubChem (100967544) PubChem (118547678) PubChem (121459604) PubChem (6916127) PubChem (124583220) PubChem (124535760) PubChem (102361707) PubChem (129010031) PubChem (132241129) PubChem (118459001) PubChem (11713633) PubChem (135228351) PubChem (122172883) PubChem (124289489) PubChem (124535759) PubChem (124785323) PubChem (129010226) PubChem (129069944) PubChem (130250494) PubChem (15558384) PubChem (15558393) PubChem (15558400) PubChem (15558397) PubChem (15558396) PubChem (15558404) PubChem (15940176) PubChem (155096397) PubChem (135219625) PubChem (162148270) PubChem (162981689) PubChem (138392495) PubChem (145978921) PubChem (146981399) PubChem (153419025) PubChem (157179210) PubChem (145082776) PubChem (162981688) PubChem (173942463) |
Sequence modifications
A, B, C: 1 - 1049 (UniProt: P31224)
| PDB | External Database | Details |
|---|---|---|
| His 1050 | - | expression tag |
| His 1051 | - | expression tag |
| His 1052 | - | expression tag |
| His 1053 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 342653.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 543.5 | |
| All* | Total formula weight | 343196.7 |
