2DFD
Crystal Structure of Human Malate Dehydrogenase Type 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Malate dehydrogenase | polymer | 342 | 36242.8 | 4 | UniProt (P40926) Pfam (PF00056) Pfam (PF02866) | Homo sapiens (human) | Malate Dehydrogenase Type 2 |
| 2 | E, K, O, T (A, B, C, D) | (2S)-2-hydroxybutanedioic acid | non-polymer | 134.1 | 4 | Chemie (LMR) | |||
| 3 | F, G, L, P, Q... (A, B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 4 | H, M, R, W (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 5 | I, N, S (A, B, C) | HISTIDINE | non-polymer | 156.2 | 3 | Chemie (HIS) | |||
| 6 | J (A) | ALANINE | non-polymer | 89.1 | 1 | Chemie (ALA) | |||
| 7 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 799 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 320 (UniProt: P40926)
| PDB | External Database | Details |
|---|---|---|
| Met -21 | - | cloning artifact |
| His -20 | - | cloning artifact |
| His -19 | - | cloning artifact |
| His -18 | - | cloning artifact |
| His -17 | - | cloning artifact |
| His -16 | - | cloning artifact |
| His -15 | - | cloning artifact |
| Ser -14 | - | cloning artifact |
| Ser -13 | - | cloning artifact |
| Gly -12 | - | cloning artifact |
| Val -11 | - | cloning artifact |
| Asp -10 | - | cloning artifact |
| Leu -9 | - | cloning artifact |
| Gly -8 | - | cloning artifact |
| Thr -7 | - | cloning artifact |
| Glu -6 | - | cloning artifact |
| Asn -5 | - | cloning artifact |
| Leu -4 | - | cloning artifact |
| Tyr -3 | - | cloning artifact |
| Phe -2 | - | cloning artifact |
| Gln -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
| Met 1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 144971.2 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 3995.8 | |
| All* | Total formula weight | 148967.0 |
