2D82
Target Structure-Based Discovery of Small Molecules that Block Human p53 and CREB Binding Protein (CBP) Association
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CREB-binding protein | polymer | 121 | 14418.5 | 1 | UniProt (Q92793) Pfam (PF00439) | Homo sapiens (human) | CBP |
| 2 | B (A) | 9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE | non-polymer | 227.3 | 1 | Chemie (TTR) |
Sequence modifications
A: 1081 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Gly 1077 | - | cloning artifact |
| Ser 1078 | - | cloning artifact |
| His 1079 | - | cloning artifact |
| Met 1080 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14418.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 227.3 | |
| All* | Total formula weight | 14645.8 |
