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2D41

X-ray crystal structure of hepatitis C virus RNA-dependent RNA polymerase in complex with non-nucleoside inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
polyproteinpolymer57063274.62UniProt (Q99AU2)
Pfam (PF00998)
Hepatitis C virusNS5B
2C, D, E, F
(A, B)
5'-ACETYL-4-{[(2,4-DIMETHYLPHENYL)SULFONYL]AMINO}-2,2'-BITHIOPHENE-5-CARBOXYLIC ACIDnon-polymer435.54Chemie (SNH)
3G, H
(A, B)
waterwater18.0695Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight126549.1
Non-Polymers*Number of molecules4
Total formula weight1742.1
All*Total formula weight128291.3
*Water molecules are not included.

238582

PDB entries from 2025-07-09

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