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2CV5

Crystal structure of human nucleosome core particle

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(I, J)
DNA (146-MER)polymer14645053.92Palindromic 146-bp human a-satellite DNA
2C, G
(A, E)
Histone H3.1polymer13615437.22UniProt (P68431)
Pfam (PF00125)
Homo sapiens (human)Histone H3
3D, H
(B, F)
Histone H4polymer10311394.42UniProt (P62805)
Pfam (PF15511)
Homo sapiens (human)
4E, I
(C, G)
Histone H2A.apolymer13014165.62UniProt (P28001)
Pfam (PF00125)
Pfam (PF16211)
UniProt (by SIFTS) (P04908)
Homo sapiens (human)Histone H2A
5F, J
(D, H)
Histone H2B Kpolymer12613921.22UniProt (O60814)
Pfam (PF00125)
Homo sapiens (human)Histone H2B, HIRA-interacting protein 1
6K, L, M, N, O...
(I, J, D)
MANGANESE (II) IONnon-polymer54.99Chemie (MN)
7S, T, V, W
(A, C, E, G)
CHLORIDE IONnon-polymer35.54Chemie (CL)
8AA, BA, CA, DA, EA...
(B, C, D, E, F...)
waterwater18.0430Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight199944.4
Non-Polymers*Number of molecules13
Total formula weight636.3
All*Total formula weight200580.7
*Water molecules are not included.

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PDB entries from 2025-07-02

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