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2CNQ

Atomic resolution structure of SAICAR-synthase from Saccharomyces cerevisiae complexed with ADP, AICAR, succinate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASEpolymer30634545.21UniProt (P27616)
Pfam (PF01259)
SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)SAICAR SYNTHETASE
2B, F
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
3C, D
(A)
AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDEnon-polymer338.22Chemie (AMZ)
4E
(A)
ADENOSINE MONOPHOSPHATEnon-polymer347.21Chemie (AMP)
5G, H
(A)
SUCCINIC ACIDnon-polymer118.12Chemie (SIN)
6I
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
7J, K, L, M
(A)
SULFATE IONnon-polymer96.14Chemie (SO4)
8N
(A)
waterwater18.0733Chemie (HOH)
Sequence modifications
A: 1 - 1 (PDB: 2CNQ)
A: 2 - 306 (UniProt: P27616)
PDBExternal DatabaseDetails
Glu 185Gly 185conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34545.2
Non-Polymers*Number of molecules12
Total formula weight2522.8
All*Total formula weight37068.0
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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