2CNQ

Atomic resolution structure of SAICAR-synthase from Saccharomyces cerevisiae complexed with ADP, AICAR, succinate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE	polymer	306	34545.2	1	UniProt (P27616) Pfam (PF01259) In PDB	SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)	SAICAR SYNTHETASE
2	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
3	A	AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE	non-polymer		338.2	2	Chemie (AMZ)
4	A	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	1	Chemie (AMP)
5	A	SUCCINIC ACID	non-polymer		118.1	2	Chemie (SIN)
6	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
7	A	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
8		water	water		18.0	733	Chemie (HOH)

Sequence modifications

A: 1 - 1 (PDB: 2CNQ)
A: 2 - 306 (UniProt: P27616)

PDB	External Database	Details
Glu 185	Gly 185	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34545.2
Non-Polymers*	Number of molecules	12
	Total formula weight	2522.8
All*	Total formula weight	37068.0

*Water molecules are not included.