Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004639 | molecular_function | phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A1314 |
| Chain | Residue |
| A | ADP1307 |
| A | HOH2518 |
| A | HOH2538 |
| A | HOH2670 |
| A | HOH2684 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A1315 |
| Chain | Residue |
| A | HOH2716 |
| A | HOH2717 |
| A | HOH2718 |
| A | HOH2719 |
| A | HOH2720 |
| A | GLU52 |
| A | ARG289 |
| A | TRP304 |
| A | SER305 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A1316 |
| Chain | Residue |
| A | LYS225 |
| A | HOH2721 |
| A | HOH2722 |
| A | HOH2723 |
| A | HOH2726 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SO4 A1317 |
| Chain | Residue |
| A | ARG73 |
| A | ASN74 |
| A | LEU76 |
| A | ASP78 |
| A | HIS110 |
| A | HOH2255 |
| A | HOH2348 |
| A | HOH2721 |
| A | HOH2724 |
| A | HOH2726 |
| A | HOH2727 |
| A | HOH2728 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A1318 |
| Chain | Residue |
| A | PHE262 |
| A | ARG287 |
| A | LYS291 |
| A | HOH2640 |
| A | HOH2641 |
| A | HOH2729 |
| A | HOH2730 |
| A | HOH2731 |
| A | HOH2733 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SIN A1312 |
| Chain | Residue |
| A | LYS5 |
| A | GLU185 |
| A | ASP186 |
| A | HOH2703 |
| A | HOH2704 |
| A | HOH2705 |
| A | HOH2706 |
| A | HOH2707 |
| A | HOH2708 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SIN A1313 |
| Chain | Residue |
| A | TYR42 |
| A | LYS131 |
| A | ARG242 |
| A | GLN261 |
| A | ARG264 |
| A | HOH2584 |
| A | HOH2681 |
| A | HOH2709 |
| A | HOH2710 |
| A | HOH2711 |
| A | HOH2712 |
| A | HOH2713 |
| site_id | AC8 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE ADP A1307 |
| Chain | Residue |
| A | GLY18 |
| A | LYS19 |
| A | VAL20 |
| A | ARG21 |
| A | ILE23 |
| A | LEU31 |
| A | PHE33 |
| A | HIS75 |
| A | HIS110 |
| A | HIS112 |
| A | LEU114 |
| A | LYS143 |
| A | GLU219 |
| A | VAL232 |
| A | ASP233 |
| A | MG1314 |
| A | HOH2078 |
| A | HOH2079 |
| A | HOH2518 |
| A | HOH2538 |
| A | HOH2670 |
| A | HOH2671 |
| A | HOH2672 |
| A | HOH2673 |
| A | HOH2674 |
| A | HOH2676 |
| A | HOH2677 |
| A | HOH2678 |
| A | HOH2684 |
| site_id | AC9 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE AMZ A1308 |
| Chain | Residue |
| A | SER240 |
| A | SER241 |
| A | ARG242 |
| A | ARG264 |
| A | ADP1311 |
| A | HOH2078 |
| A | HOH2539 |
| A | HOH2679 |
| A | HOH2680 |
| A | HOH2681 |
| A | HOH2682 |
| A | HOH2683 |
| A | HOH2684 |
| A | HOH2685 |
| A | HOH2686 |
| A | HOH2696 |
| A | HOH2698 |
| A | GLU118 |
| A | ILE120 |
| A | ARG122 |
| A | GLY127 |
| A | SER128 |
| A | ASP171 |
| A | ASP215 |
| A | LYS217 |
| A | ASP239 |
| site_id | BC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE AMZ A1309 |
| Chain | Residue |
| A | GLU62 |
| A | LYS66 |
| A | VAL77 |
| A | ILE79 |
| A | ILE85 |
| A | LEU107 |
| A | LEU108 |
| A | ASP186 |
| A | HOH2270 |
| A | HOH2460 |
| A | HOH2687 |
| A | HOH2688 |
| A | HOH2689 |
| A | HOH2690 |
| A | HOH2691 |
| A | HOH2692 |
| A | HOH2693 |
| A | HOH2694 |
| A | HOH2695 |
| site_id | BC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE AMP A1310 |
| Chain | Residue |
| A | GLU62 |
| A | LYS66 |
| A | VAL77 |
| A | ILE79 |
| A | ILE85 |
| A | SER106 |
| A | LEU107 |
| A | LEU108 |
| A | ASP186 |
| A | HOH2194 |
| A | HOH2270 |
| A | HOH2460 |
| A | HOH2689 |
| A | HOH2690 |
| A | HOH2691 |
| A | HOH2692 |
| A | HOH2693 |
| A | HOH2694 |
| A | HOH2695 |
| site_id | BC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ADP A1311 |
| Chain | Residue |
| A | LYS19 |
| A | SER40 |
| A | ALA41 |
| A | TYR42 |
| A | ASP43 |
| A | HIS170 |
| A | ASP171 |
| A | LYS260 |
| A | ARG264 |
| A | AMZ1308 |
| A | HOH2131 |
| A | HOH2136 |
| A | HOH2429 |
| A | HOH2682 |
| A | HOH2683 |
| A | HOH2686 |
| A | HOH2696 |
| A | HOH2698 |
| A | HOH2699 |
| A | HOH2700 |
| A | HOH2701 |
| A | HOH2710 |
Functional Information from PROSITE/UniProt
| site_id | PS01057 |
| Number of Residues | 15 |
| Details | SAICAR_SYNTHETASE_1 SAICAR synthetase signature 1. LIPLEvIVRgyiTGS |
| Chain | Residue | Details |
| A | LEU114-SER128 | |
| site_id | PS01058 |
| Number of Residues | 9 |
| Details | SAICAR_SYNTHETASE_2 SAICAR synthetase signature 2. IADtKFEFG |
| Chain | Residue | Details |
| A | ILE213-GLY221 | |
Functional Information from SwissProt/UniProt
