2CNK

Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CASPASE-3 P17 SUBUNIT	polymer	147	16639.9	1	UniProt (P42574) Pfam (PF00656) In PDB	HOMO SAPIENS (HUMAN)	CASPASE-3 SUBUNIT P17
2	B	CASPASE-3 P12 SUBUNIT	polymer	103	11981.7	1	UniProt (P42574) Pfam (PF00656) In PDB	HOMO SAPIENS (HUMAN)	CASPASE-3 SUBUNIT P12
3	I	AZA-PEPTIDE EXPOXIDE	polymer	5	792.2	1	BIRD (PRD_000673)	SYNTHETIC CONSTRUCT
4		water	water		18.0	403	Chemie (HOH)

Sequence modifications

B: 175 - 175 (PDB: 2CNK)
B: 176 - 277 (UniProt: P42574)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	29413.8
All*	Total formula weight	29413.8

*Water molecules are not included.