2CK2

Structure of core-swapped mutant of fibronectin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	HUMAN FIBRONECTIN	polymer	96	10171.3	2	UniProt (P02751) Pfam (PF00041) In PDB	HOMO SAPIENS (HUMAN)	FN, COLD-INSOLUBLE GLOBULIN, CIG
2	A, B	ACETYL GROUP	non-polymer		44.1	2	Chemie (ACE)
3		water	water		18.0	109	Chemie (HOH)

Sequence modifications

A, B: 1 - 96 (UniProt: P02751)

PDB	External Database	Details
Ile 8	Leu 1454	engineered mutation
Val 13	Ala 1459	engineered mutation
Ala 18	Leu 1464	engineered mutation
Ile 29	Val 1475	engineered mutation
Ile 32	Tyr 1478	engineered mutation
Leu 34	Ile 1480	engineered mutation
Ile 48	Phe 1494	engineered mutation
Leu 50	Val 1496	engineered mutation
Tyr 57	Ala 1503	engineered mutation
Thr 66	Val 1512	engineered mutation
Leu 72	Val 1518	engineered mutation
Ser 74	Ala 1520	engineered mutation
Ala 88	Ile 1534	engineered mutation
Phe 92	Tyr 1538	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	20342.6
Non-Polymers*	Number of molecules	2
	Total formula weight	88.1
All*	Total formula weight	20430.7

*Water molecules are not included.