2CF8
Complex of recombinant human thrombin with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | THROMBIN HEAVY CHAIN | polymer | 257 | 29594.1 | 1 | UniProt (P00734) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | |
| 2 | B (I) | HIRUDIN IIIA | polymer | 11 | 1396.5 | 1 | UniProt (P28508) BIRD (PRD_000481) | HIRUDO MEDICINALIS | |
| 3 | C (L) | THROMBIN LIGHT CHAIN | polymer | 28 | 3303.7 | 1 | UniProt (P00734) Pfam (PF09396) | HOMO SAPIENS (HUMAN) | |
| 4 | D (H) | 4- [(1R,3AS,4R,8AS,8BR)- 2- (4-CHLOROBENZYL)- 1- ISOPROPYL- 3- OXODECAHYDROPYRROLO[3,4- A]PYRROLIZIN- 4- YL]BENZENECARBOXIMIDAMIDE | non-polymer | 451.0 | 1 | Chemie (ESH) | |||
| 5 | E (H) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F (H) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | G, H, I (H, I, L) | water | water | 18.0 | 397 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34294.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 514.1 | |
| All* | Total formula weight | 34808.3 |
