2C6Q

Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP and NADPH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	GMP REDUCTASE 2	polymer	351	38157.5	8	UniProt (Q9P2T1) Pfam (PF00478) In PDB	HOMO SAPIENS (HUMAN)	GUANOSINE MONOPHOSPHATE REDUCTASE 2, GUANOSINE 5'-MONOPHOSPHATE OXIDOREDUCTASE 2
2	A, B, C, D, E...	INOSINIC ACID	non-polymer		348.2	8	Chemie (IMP)
3	A, B, C, D, E...	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	7	Chemie (NDP)
4		water	water		18.0	2569	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: -9 - 9 (PDB: 2C6Q)
A, B, C, D, E, F, G, H: 10 - 341 (UniProt: Q9P2T1)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	305260.3
Non-Polymers*	Number of molecules	15
	Total formula weight	8003.6
All*	Total formula weight	313263.9

*Water molecules are not included.