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2C60

crystal structure of human mitogen-activated protein kinase kinase kinase 3 isoform 2 phox domain at 1.25 A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 ISOFORM 2polymer11113144.11UniProt (Q99759)
Pfam (PF00564)
HOMO SAPIENS (HUMAN)MAPK/ERK KINASE KINASE 3, MEK KINASE 3, MEKK 3
2B
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D
(A)
waterwater18.0128Chemie (HOH)
Sequence modifications
A: -23 - -1 (PDB: 2C60)
A: 37 - 124 (UniProt: Q99759)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight13144.1
Non-Polymers*Number of molecules2
Total formula weight132.2
All*Total formula weight13276.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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