2C5O
Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | CELL DIVISION PROTEIN KINASE 2 | polymer | 298 | 33976.5 | 2 | UniProt (P24941) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | CYCLIN-DEPENDENT KINASE 2, P33 PROTEIN KINASE |
| 2 | B, D (B, D) | CYCLIN A2 | polymer | 260 | 29867.5 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) | HOMO SAPIENS (HUMAN) | CYCLIN A |
| 3 | E, F (A, C) | 4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)PYRIMIDIN-2-AMINE | non-polymer | 206.3 | 2 | Chemie (CK2) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 725 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 127688.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 412.5 | |
| All* | Total formula weight | 128100.5 |
