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2C01

Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(X)
NONSECRETORY RIBONUCLEASEpolymer13515611.81UniProt (P10153)
Pfam (PF00074)
HOMO SAPIENS (HUMAN)EOSINOPHIL-DERIVED NEUROTOXIN, RIBONUCLEASE US, RNASE UPI-2, RIBONUCLEASE 2, RNASE 2
2B
(X)
ACETIC ACIDnon-polymer60.11Chemie (ACY)
3C
(X)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
4D
(X)
waterwater18.0238Chemie (HOH)
Sequence modifications
X: 0 - 0 (PDB: 2C01)
X: 1 - 134 (UniProt: P10153)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight15611.8
Non-Polymers*Number of molecules2
Total formula weight567.2
All*Total formula weight16179.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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