2BXW

CRYSTAL STRUCTURE OF RHOGDI Lys(135,138,141)Tyr MUTANT

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	RHO GDP-DISSOCIATION INHIBITOR 1	polymer	141	16199.4	2	UniProt (P52565) Pfam (PF02115)	HOMO SAPIENS (HUMAN)	RHO GDI 1, RHO-GDI ALPHA
2	C, D (A)	FORMIC ACID	non-polymer		46.0	2	Chemie (FMT)
3	E (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
4	F, G (A, B)	water	water		18.0	213	Chemie (HOH)

Sequence modifications

A, B: 64 - 66 (PDB: 2BXW)
A, B: 67 - 204 (UniProt: P52565)

PDB	External Database	Details
Tyr 135	Lys 135	engineered mutation
Tyr 138	Lys 138	engineered mutation
Tyr 141	Lys 141	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	32398.7
Non-Polymers*	Number of molecules	3
	Total formula weight	214.2
All*	Total formula weight	32612.9

*Water molecules are not included.