2BUJ
Crystal structure of the human Serine-threonine Kinase 16 in complex with staurosporine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | SERINE/THREONINE-PROTEIN KINASE 16 | polymer | 317 | 36306.5 | 2 | UniProt (O75716) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | HUMAN SERINE THREONINE KINASE 16, PROTEIN KINASE PKL12, MYRISTOYLATED AND PALMITOYLATED SERINE/THREONINE KINASE, MPSK, TGF-BETA STIMULATED FACTOR 1, TSF-1, HPSK |
| 2 | C, F (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 3 | D, E, G, H (A, B) | STAUROSPORINE | non-polymer | 466.5 | 4 | Chemie (STU) PubChem (5279) PubChem (71203703) PubChem (42610657) PubChem (44259) PubChem (44299148) PubChem (49831000) PubChem (25322871) PubChem (28684983) PubChem (44120114) PubChem (44537813) PubChem (46864193) PubChem (68262703) PubChem (68306294) PubChem (451705) PubChem (73953205) PubChem (86306248) PubChem (358479) PubChem (5280487) PubChem (5459111) PubChem (5311103) PubChem (6711321) PubChem (9956178) PubChem (6419748) PubChem (9804568) PubChem (122130844) PubChem (12046017) PubChem (9937179) PubChem (143163481) PubChem (143224059) PubChem (143494026) PubChem (162978898) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
A, B: -10 - 12 (PDB: 2BUJ)
A, B: 306 - 306 (PDB: 2BUJ)
A, B: 13 - 305 (UniProt: O75716)
A, B: 306 - 306 (PDB: 2BUJ)
A, B: 13 - 305 (UniProt: O75716)
| PDB | External Database | Details |
|---|---|---|
| His 19 | Arg 18 | engineered mutation |
| Trp 266 | Arg 265 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72613.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1937.0 | |
| All* | Total formula weight | 74550.0 |
