2BUB

Crystal Structure Of Human Dipeptidyl Peptidase IV (CD26) in Complex with a Reversed Amide Inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DIPEPTIDYL PEPTIDASE 4	polymer	728	84462.6	2	UniProt (P27487) Pfam (PF00930) Pfam (PF00326)	HOMO SAPIENS (HUMAN)	DIPEPTIDYL PEPTIDASE IV, DPP IV, T-CELL ACTIVATION ANTIGEN CD26, TP103, ADENOSINE DEAMINASE COMPLEXING PROTEIN-2
2	C, D, E, F, H... (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
3	G, L (A, B)	N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE	non-polymer		383.5	2	Chemie (FPB)
4	M, N (A, B)	water	water		18.0	320	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	168925.2
Non-Polymers*	Number of molecules	10
	Total formula weight	2536.6
All*	Total formula weight	171461.8

*Water molecules are not included.