2BU7

crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2	polymer	394	44647.7	1	UniProt (Q15119) Pfam (PF10436) Pfam (PF02518)	HOMO SAPIENS (HUMAN)	PYRUVATE DEHYDROGENASE KINASE ISOFORM 2
2	B (A)	N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE	non-polymer		360.9	1	Chemie (TF3)
3	C (A)	water	water		18.0	152	Chemie (HOH)

Sequence modifications

A: 6 - 7 (PDB: 2BU7)
A: 8 - 399 (UniProt: Q15119)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44647.7
Non-Polymers*	Number of molecules	1
	Total formula weight	360.9
All*	Total formula weight	45008.6

*Water molecules are not included.