2BR8
Crystal Structure of Acetylcholine-binding Protein (AChBP) from Aplysia californica in complex with an alpha-conotoxin PnIA variant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E | SOLUBLE ACETYLCHOLINE RECEPTOR | polymer | 217 | 24688.6 | 5 | UniProt (Q8WSF8) Pfam (PF02931) In PDB | APLYSIA CALIFORNICA (CALIFORNIA SEA HARE) | ACETYLCHOLINE-BINDING PROTEIN |
2 | F, G, H, I, J | ALPHA-CONOTOXIN PNIA | polymer | 17 | 1682.0 | 5 | UniProt (P50984) In PDB | CONUS PENNACEUS | ALPHA-PNIA |
3 | C, E, F, G, I | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
4 | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 217 (UniProt: Q8WSF8)
F, G, H, I, J: 1 - 16 (UniProt: P50984)
F, G, H, I, J: 17 - 17 (PDB: 2BR8)
PDB | External Database | Details |
---|---|---|
Val 41 | Ala 60 | conflict |
Val 136 | Ala 155 | conflict |
PDB | External Database | Details |
---|---|---|
Leu 10 | Ala 10 | engineered mutation |
Lys 14 | Asp 14 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 131853.0 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 480.3 | |
All* | Total formula weight | 132333.3 |