2BPO
Crystal structure of the yeast CPR triple mutant: D74G, Y75F, K78A.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NADPH-CYTOCHROM P450 REDUCTASE | polymer | 682 | 75710.9 | 2 | UniProt (P16603) Pfam (PF00258) Pfam (PF00667) Pfam (PF00175) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | CPR, P450R |
| 2 | C, H (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 3 | D, I (A, B) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 2 | Chemie (FMN) | |||
| 4 | E, J (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 5 | F, G, K (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A, B: 10 - 46 (PDB: 2BPO)
A, B: 47 - 691 (UniProt: P16603)
A, B: 47 - 691 (UniProt: P16603)
| PDB | External Database | Details |
|---|---|---|
| Gly 74 | Asp 73 | engineered mutation |
| Phe 75 | Tyr 74 | engineered mutation |
| Ala 78 | Lys 77 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 151421.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 4258.8 | |
| All* | Total formula weight | 155680.6 |
