2BKK
Crystal structure of Aminoglycoside Phosphotransferase APH(3')-IIIa in complex with the inhibitor AR_3a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE | polymer | 264 | 30979.9 | 2 | UniProt (P00554) Pfam (PF01636) UniProt (by SIFTS) (P0A3Y5) In PDB | ENTEROCOCCUS FAECALIS | APH IIIA, KANAMYCIN KINASE TYPE III, NEOMYCIN-KANAMYCIN PHOSPHOTRANSFERASE TYPE III, APH(3')III |
| 2 | B, D | DESIGNED ANKYRIN REPEAT INHIBITOR AR_3A | polymer | 169 | 18602.8 | 2 | SYNTHETIC CONSTRUCT | ||
| 3 | A, C | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 347 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 264 (UniProt: P00554)
| PDB | External Database | Details |
|---|---|---|
| Ser 19 | Cys 19 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 99165.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 951.6 | |
| All* | Total formula weight | 100117.1 |
