2BE6
2.0 A crystal structure of the CaV1.2 IQ domain-Ca/CaM complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, B, C) | Calmodulin 2 | polymer | 150 | 16965.7 | 3 | UniProt (Q53S29) Pfam (PF13499) UniProt (by SIFTS) (P0DP23) | Homo sapiens (human) | |
| 2 | B, D, F (D, E, F) | Voltage-dependent L-type calcium channel alpha-1C subunit | polymer | 37 | 4373.1 | 3 | UniProt (Q13933) UniProt (by SIFTS) (Q13936) | Homo sapiens (human) | Voltage-gated calcium channel alpha subunit Cav1.2, Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle |
| 3 | G, H, I, J, L... (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 12 | Chemie (CA) | |||
| 4 | K, P, U (A, B, C) | NICKEL (II) ION | non-polymer | 58.7 | 3 | Chemie (NI) | |||
| 5 | V, W, X, Y, Z (A, D, B, C, F) | water | water | 18.0 | 254 | Chemie (HOH) |
Sequence modifications
D, E, F: 1611 - 1644 (UniProt: Q13933)
| PDB | External Database | Details |
|---|---|---|
| Gly 1608 | - | cloning artifact |
| His 1609 | - | cloning artifact |
| Met 1610 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 64016.4 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 657.0 | |
| All* | Total formula weight | 64673.4 |
