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2BCU

DNA polymerase lambda in complex with a DNA duplex containing an unpaired Damp and a T:T mismatch

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(D)
5'-D(P*GP*CP*CP*G)-3'polymer41191.81
2B
(P)
5'-D(*CP*AP*GP*TP*TP*CP*G)-3'polymer72113.41
3C
(T)
5'-D(*CP*GP*GP*CP*CP*GP*AP*TP*AP*CP*TP*G)-3'polymer123663.41
4D
(A)
DNA polymerase lambdapolymer33537479.81UniProt (Q9UGP5)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (human)Pol Lambda, DNA polymerase kappa, DNA polymerase beta-2, Pol beta2
5E, F, G
(A)
SODIUM IONnon-polymer23.03Chemie (NA)
6H
(A)
PYROPHOSPHATEnon-polymer178.01Chemie (PPV)
7I, J, K, L
(D, P, T, A)
waterwater18.0245Chemie (HOH)
Sequence modifications
A: 242 - 575 (UniProt: Q9UGP5)
PDBExternal DatabaseDetails
Met 241-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight44448.4
Non-Polymers*Number of molecules4
Total formula weight246.9
All*Total formula weight44695.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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