2BCK
Crystal Structure of HLA-A*2402 Complexed with a telomerase peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | HLA class I histocompatibility antigen, A-24 alpha chain | polymer | 294 | 33720.2 | 2 | UniProt (P05534) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) In PDB | Homo sapiens (human) | MHC class I antigen A*24, Aw-24, A-9, HLA-A*2402 Heavy Chain, alpha chain |
2 | B, E | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (human) | HLA-A*2402 Light Chain |
3 | C, F | Telomerase reverse transcriptase | polymer | 9 | 1028.2 | 2 | UniProt (O14746) In PDB | Telomerase catalytic subunit, HEST2, Telomerase-associated protein 2, TP2 | |
4 | A, B, D, E | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
5 | A, B, D, E | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
6 | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 276 (UniProt: P05534)
B, E: 1 - 99 (UniProt: P61769)
PDB | External Database | Details |
---|---|---|
Gly 277 | - | cloning artifact |
Ser 278 | - | cloning artifact |
Gly 279 | - | cloning artifact |
Gly 280 | - | cloning artifact |
Gly 281 | - | cloning artifact |
Leu 282 | - | cloning artifact |
Asn 283 | - | cloning artifact |
Asp 284 | - | cloning artifact |
Ile 285 | - | cloning artifact |
Phe 286 | - | cloning artifact |
Glu 287 | - | cloning artifact |
Ala 288 | - | cloning artifact |
Gln 289 | - | cloning artifact |
Lys 290 | - | cloning artifact |
Ile 291 | - | cloning artifact |
Glu 292 | - | cloning artifact |
Trp 293 | - | cloning artifact |
His 294 | - | cloning artifact |
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 93255.6 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1136.9 | |
All* | Total formula weight | 94392.5 |