2BC9
Crystal-structure of the N-terminal large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with non-hydrolysable GTP analogue GppNHp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interferon-induced guanylate-binding protein 1 | polymer | 328 | 37078.4 | 1 | UniProt (P32455) Pfam (PF02263) | Homo sapiens (human) | GTP-binding protein 1, Guanine nucleotide-binding protein 1, HuGBP-1 |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 4 | D (A) | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
A: 1 - 317 (UniProt: P32455)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | cloning artifact |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| Met -3 | - | cloning artifact |
| Arg -2 | - | cloning artifact |
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37078.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 546.5 | |
| All* | Total formula weight | 37624.9 |
