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2B3Y

Structure of a monoclinic crystal form of human cytosolic aconitase (IRP1)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Iron-responsive element binding protein 1polymer88898374.42UniProt (P21399)
Pfam (PF00330)
Pfam (PF00694)
Homo sapiens (human)IRE-BP 1, Iron regulatory protein 1, IRP1, Ferritin repressor protein, Aconitate hydratase, Citrate hydro-lyase, Aconitase
2C, G, H
(A, B)
ACETATE IONnon-polymer59.03Chemie (ACT)
3D, I
(A, B)
IRON/SULFUR CLUSTERnon-polymer351.62Chemie (SF4)
4E, F
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
5J
(B)
FORMIC ACIDnon-polymer46.01Chemie (FMT)
6K, L
(A, B)
waterwater18.0970Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight196748.8
Non-Polymers*Number of molecules8
Total formula weight1110.6
All*Total formula weight197859.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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