2B2T

Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and phosphothreonine 3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Chromodomain-helicase-DNA-binding protein 1	polymer	187	22362.4	2	UniProt (O14646) Pfam (PF00385)	Homo sapiens (human)	CHD-1
2	C (C)	Chromodomain-helicase-DNA-binding protein 1	polymer	115	13835.0	1	UniProt (O14646) Pfam (PF00385)	Homo sapiens (human)	CHD-1
3	D (D)	Histone H3 tail	polymer	20	2362.6	1	UniProt (P68431)
4	E, F, G, H (A, B, C, D)	water	water		18.0	258	Chemie (HOH)

Sequence modifications

A, B: 10 - 185 (UniProt: O14646)

PDB	External Database	Details
Mse 1	-	SEE REMARK 999
Lys 2	-	cloning artifact
Lys 3	-	cloning artifact
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Mse 20	Met 278	modified residue
Mse 88	Met 346	modified residue
Mse 178	Cys 436	SEE REMARK 999
Lys 186	-	cloning artifact
Lys 187	-	cloning artifact

C: 10 - 115 (UniProt: O14646)

PDB	External Database	Details
Mse 1	-	SEE REMARK 999
Lys 2	-	cloning artifact
Lys 3	-	cloning artifact
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Mse 20	Met 278	modified residue
Mse 88	Met 346	modified residue

D: 1 - 19 (UniProt: P68431)

PDB	External Database	Details
Tpo 3	Thr 3	modified residue
M3l 4	Lys 4	modified residue
Tyr 20	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	60922.4
All*	Total formula weight	60922.4

*Water molecules are not included.