2B2A

Crystal Structure of the TEN domain of the Telomerase Reverse Transcriptase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Telomerase reverse transcriptase	polymer	199	23621.8	3	UniProt (O77448) Pfam (PF11474)	Tetrahymena thermophila	Telomerase catalytic subunit, Telomerase subunit P133
2	D, E, F (A, B, C)	water	water		18.0	96	Chemie (HOH)

Sequence modifications

A, B, C: 2 - 191 (UniProt: O77448)

PDB	External Database	Details
Met -7	-	cloning artifact
Lys -6	-	cloning artifact
Lys -5	-	cloning artifact
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Met 87	Leu 87	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	70865.5
All*	Total formula weight	70865.5

*Water molecules are not included.