2B23
Human estrogen receptor alpha ligand-binding domain and a glucocorticoid receptor-interacting protein 1 NR box II peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Estrogen receptor | polymer | 257 | 29527.9 | 2 | UniProt (P03372) Pfam (PF00104) In PDB | Homo sapiens (human) | ER, Estradiol receptor, ER-alpha |
2 | C, D | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 2 | UniProt (Q15596) In PDB | NCoA-2, Transcriptional intermediary factor 2 | |
3 | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A, B: 298 - 554 (UniProt: P03372)
PDB | External Database | Details |
---|---|---|
Cme 381 | Cys 381 | modified residue |
Cme 417 | Cys 417 | modified residue |
Cme 530 | Cys 530 | modified residue |
Ser 537 | Tyr 537 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 62215.5 | |
All* | Total formula weight | 62215.5 |