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2B07

Crystal structure of PTP1B with Tricyclic Thiophene inhibitor.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase, non-receptor type 1polymer29934833.71UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)Protein-tyrosine phosphatase 1B, PTP-1B
2B
(A)
6-{[1-(BENZYLSULFONYL)PIPERIDIN-4-YL]AMINO}-3-(CARBOXYMETHOXY)THIENO[3,2-B][1]BENZOTHIOPHENE-2-CARBOXYLIC ACIDnon-polymer560.71Chemie (598)
3C
(A)
waterwater18.0176Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34833.7
Non-Polymers*Number of molecules1
Total formula weight560.7
All*Total formula weight35394.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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