2AZ9
HIV-1 Protease NL4-3 1X mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEASE RETROPEPSIN | polymer | 99 | 10803.8 | 1 | UniProt (P03367) Pfam (PF00077) | Human immunodeficiency virus 1 | HIV-1 PROTEASE |
| 2 | B (A) | benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate | non-polymer | 909.1 | 1 | BIRD (PRD_000434) Chemie (3TL) | |||
| 3 | C (A) | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A: 1 - 99 (UniProt: P03367)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 75 | variant |
| Asn 37 | Ser 105 | variant |
| Ala 82 | Val 150 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10803.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 909.1 | |
| All* | Total formula weight | 11712.9 |
