2AXI
HDM2 in complex with a beta-hairpin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin-protein ligase E3 Mdm2 | polymer | 115 | 13364.2 | 1 | UniProt (Q9UMT8) Pfam (PF02201) UniProt (by SIFTS) (Q00987) | Homo sapiens (human) | p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2 |
| 2 | B (B) | cyclic 8-mer peptide | polymer | 10 | 1399.9 | 1 | BIRD (PRD_000326) | ||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | 3[N-MORPHOLINO]PROPANE SULFONIC ACID | non-polymer | 209.3 | 1 | Chemie (MPO) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A: 17 - 125 (UniProt: Q9UMT8)
| PDB | External Database | Details |
|---|---|---|
| His 126 | - | expression tag |
| His 127 | - | expression tag |
| His 128 | - | expression tag |
| His 129 | - | expression tag |
| His 130 | - | expression tag |
| His 131 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 14764.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 401.4 | |
| All* | Total formula weight | 15165.5 |
