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2ATH

Crystal structure of the ligand binding domain of human PPAR-gamma im complex with an agonist

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Peroxisome proliferator activated receptor gammapolymer27130997.02UniProt (P37231)
Pfam (PF00104)
Homo sapiens (human)PPAR-gamma
2C, D
(A, B)
2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACIDnon-polymer476.42Chemie (3EA)
3E, F
(A, B)
waterwater18.0123Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight61994.0
Non-Polymers*Number of molecules2
Total formula weight952.9
All*Total formula weight62946.9
*Water molecules are not included.

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PDB entries from 2024-11-06

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