2ARR

Human plasminogen activator inhibitor-2.[loop (66-98) deletion mutant] complexed with peptide n-acetyl-teaaagmggvmtgr-oh

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Plasminogen activator inhibitor-2	polymer	382	42986.9	1	UniProt (P05120) Pfam (PF00079)	Homo sapiens (human)	PAI-2, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor
2	B (P)	14-mer from Plasminogen activator inhibitor-2	polymer	15	1335.5	1	UniProt (P05120)	Homo sapiens (human)	PAI-2, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor
3	C, D (A, P)	water	water		18.0	326	Chemie (HOH)

Sequence modifications

A: 1 - 415 (UniProt: P05120)

PDB	External Database	Details
Ser 56	Lys 56	conflict
-	Asn 66	deletion
-	Ala 67	deletion
-	Val 68	deletion
-	Thr 69	deletion
-	Pro 70	deletion
-	Met 71	deletion
-	Thr 72	deletion
-	Pro 73	deletion
-	Glu 74	deletion
-	Asn 75	deletion
-	Phe 76	deletion
-	Thr 77	deletion
-	Ser 78	deletion
-	Cys 79	deletion
-	Gly 80	deletion
-	Phe 81	deletion
-	Met 82	deletion
-	Gln 83	deletion
-	Gln 84	deletion
-	Ile 85	deletion
-	Gln 86	deletion
-	Lys 87	deletion
-	Gly 88	deletion
-	Ser 89	deletion
-	Tyr 90	deletion
-	Pro 91	deletion
-	Asp 92	deletion
-	Ala 93	deletion
-	Ile 94	deletion
-	Leu 95	deletion
-	Gln 96	deletion
-	Ala 97	deletion
-	Gln 98	deletion
Phe 220	Tyr 220	conflict

P: 345 - 358 (UniProt: P05120)

PDB	External Database	Details
Met 351	Thr 373	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44322.4
All*	Total formula weight	44322.4

*Water molecules are not included.