2AQK
Crystal structure of Isoniazid-resistant S94A Enoyl-ACP(CoA) reductase mutant enzyme from Mycobacterium tuberculosis in complex with NADH
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 269 | 28538.8 | 1 | UniProt (P0A5Y6) Pfam (PF13561) UniProt (by SIFTS) (P9WGR1) In PDB | Mycobacterium tuberculosis | NADH-dependent enoyl-ACP reductase |
2 | A | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 1 | Chemie (NAI) | |||
3 | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A: 1 - 269 (UniProt: P0A5Y6)
PDB | External Database | Details |
---|---|---|
Ala 94 | Ser 94 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 28538.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 665.4 | |
All* | Total formula weight | 29204.2 |