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2AOX

Histamine Methyltransferase (Primary Variant T105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Histamine N-methyltransferasepolymer29233333.02UniProt (P50135)
Pfam (PF13489)
Homo sapiens (human)HMT
2C, D
(A, B)
TACRINEnon-polymer198.32Chemie (THA)
3E, F
(A, B)
waterwater18.09Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight66666.0
Non-Polymers*Number of molecules2
Total formula weight396.5
All*Total formula weight67062.6
*Water molecules are not included.

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PDB entries from 2025-07-16

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