2AO6
Crystal structure of the human androgen receptor ligand binding domain bound with TIF2(iii) 740-753 peptide and R1881
Replaces: 1XQ2Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | androgen receptor | polymer | 249 | 29046.1 | 1 | UniProt (P10275) Pfam (PF00104) In PDB | Homo sapiens (human) | DIHYDROTESTOSTERONE RECEPTOR |
2 | B | 14-mer fragment of Nuclear receptor coactivator 2 | polymer | 25 | 2810.2 | 1 | UniProt (Q15596) In PDB | NCOA-2; TRANSCRIPTIONAL INTERMEDIARY FACTOR 2 | |
3 | A | (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE | non-polymer | 284.4 | 1 | Chemie (R18) | |||
4 | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence modifications
B: 727 - 740 (UniProt: Q15596)
PDB | External Database | Details |
---|---|---|
Gly 741 | - | insertion |
Asn 742 | - | insertion |
Ala 743 | - | insertion |
Ala 744 | - | insertion |
Leu 745 | - | insertion |
Arg 746 | - | insertion |
Tyr 747 | - | insertion |
Leu 748 | - | insertion |
Leu 749 | - | insertion |
Gly 750 | - | insertion |
Ala 751 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 31856.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 284.4 | |
All* | Total formula weight | 32140.7 |