2AO6
Crystal structure of the human androgen receptor ligand binding domain bound with TIF2(iii) 740-753 peptide and R1881
Replaces: 1XQ2Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | androgen receptor | polymer | 249 | 29046.1 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (human) | DIHYDROTESTOSTERONE RECEPTOR |
| 2 | B (B) | 14-mer fragment of Nuclear receptor coactivator 2 | polymer | 25 | 2810.2 | 1 | UniProt (Q15596) | NCOA-2; TRANSCRIPTIONAL INTERMEDIARY FACTOR 2 | |
| 3 | C (A) | (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE | non-polymer | 284.4 | 1 | Chemie (R18) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence modifications
B: 727 - 740 (UniProt: Q15596)
| PDB | External Database | Details |
|---|---|---|
| Gly 741 | - | insertion |
| Asn 742 | - | insertion |
| Ala 743 | - | insertion |
| Ala 744 | - | insertion |
| Leu 745 | - | insertion |
| Arg 746 | - | insertion |
| Tyr 747 | - | insertion |
| Leu 748 | - | insertion |
| Leu 749 | - | insertion |
| Gly 750 | - | insertion |
| Ala 751 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31856.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 284.4 | |
| All* | Total formula weight | 32140.7 |
