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2ANL

X-ray crystal structure of the aspartic protease plasmepsin 4 from the malarial parasite plasmodium malariae bound to an allophenylnorstatine based inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
plasmepsin IVpolymer32737130.82UniProt (O60990)
Pfam (PF00026)
Plasmodium malariae
2C, D
(A, B)
(4R)-3-{(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl}-5,5-dimethyl-N-(2-methylbenzyl)-1,3-thiazolidine-4-carboxamidenon-polymer575.72BIRD (PRD_000566)
Chemie (JE2)
3E, F
(A, B)
waterwater18.014Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight74261.7
Non-Polymers*Number of molecules2
Total formula weight1151.4
All*Total formula weight75413.1
*Water molecules are not included.

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PDB entries from 2025-11-05

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