2AMD
Crystal Structure Of SARS_CoV Mpro in Complex with an Inhibitor N9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3C-like proteinase | polymer | 311 | 34288.1 | 2 | UniProt (P59641) Pfam (PF05409) UniProt (by SIFTS) (P0C6X7) | SARS coronavirus | sars main protease, 3CL-PRO |
| 2 | C, D (A, B) | N-(3-FUROYL)-D-VALYL-L-VALYL-N~1~-((1R,2Z)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-D-LEUCINAMIDE | non-polymer | 631.8 | 2 | Chemie (9IN) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 401 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 306 (UniProt: P59641)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | cloning artifact |
| Pro -3 | - | cloning artifact |
| Leu -2 | - | cloning artifact |
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68576.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1263.5 | |
| All* | Total formula weight | 69839.7 |
