2AJQ
Structure of replicative DNA polymerase provides insigts into the mechanisms for processivity, frameshifting and editing
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (P, X) | DNA Primer | polymer | 22 | 6739.4 | 2 | |||
| 2 | B, D (T, Z) | DNA Template | polymer | 26 | 8026.1 | 2 | |||
| 3 | E, G (A, F) | T7 DNA polymerase | polymer | 704 | 79703.6 | 2 | UniProt (P00581) Pfam (PF00476) | Enterobacteria phage T7 | |
| 4 | F, H (B, I) | thioredoxin 1 | polymer | 108 | 11687.4 | 2 | UniProt (P0AA25) Pfam (PF00085) | Escherichia coli | TRX1; TRX |
| 5 | I, J, K, L, M... (P, T, X, Z, A...) | water | water | 18.0 | 414 | Chemie (HOH) |
Sequence modifications
A, F: 1 - 704 (UniProt: P00581)
| PDB | External Database | Details |
|---|---|---|
| Ala 5 | Asp 5 | engineered mutation |
| Ala 7 | Glu 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 212313.0 | |
| All* | Total formula weight | 212313.0 |
