2AJL

X-ray Structure of Novel Biaryl-Based Dipeptidyl peptidase IV inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (I, J)	Dipeptidyl peptidase 4	polymer	728	84462.6	2	UniProt (P27487) Pfam (PF00930) Pfam (PF00326)	Homo sapiens (human)	Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, Adenosine deaminase complexing protein 2, ADABP
2	C, D, E, F, G... (I, J)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	14	Chemie (NAG)
3	H, R (I, J)	1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE	non-polymer		323.4	2	Chemie (JNH)
4	S, T (I, J)	water	water		18.0	403	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	168925.2
Non-Polymers*	Number of molecules	16
	Total formula weight	3743.8
All*	Total formula weight	172669.0

*Water molecules are not included.