2ACX
Crystal Structure of G protein coupled receptor kinase 6 bound to AMPPNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | G protein-coupled receptor kinase 6 | polymer | 576 | 66010.7 | 2 | UniProt (P43250) Pfam (PF00615) Pfam (PF00069) | Homo sapiens (human) | G protein-coupled receptor kinase GRK6 |
| 2 | C, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, G (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | E, H (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 576 (UniProt: P43250)
| PDB | External Database | Details |
|---|---|---|
| Asn 60 | Gln 60 | SEE REMARK 999 |
| Asn 104 | Gln 104 | SEE REMARK 999 |
| Ser 561 | Cys 561 | engineered mutation |
| Ser 562 | Cys 562 | engineered mutation |
| Ser 565 | Cys 565 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 132021.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1250.9 | |
| All* | Total formula weight | 133272.3 |
