2AB4
Dissecting the Roles of a Strictly Conserved Tyrosine in Substrate Recognition and Catalysis by Pseudouridine 55 Synthase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | 5'-R(*CP*CP*AP*CP*GP*GP*UP*(FHU)P*CP*GP*AP*AP*UP*CP*CP*GP*UP*GP*GP*C)-3' | polymer | 20 | 6410.8 | 1 | |||
| 2 | B (A) | tRNA pseudouridine synthase B | polymer | 309 | 35528.2 | 1 | UniProt (Q9WZW0) Pfam (PF01509) Pfam (PF16198) Pfam (PF01472) | Thermotoga maritima | tRNA pseudouridine 55 synthase, Psi55 synthase, tRNA-uridine isomerase, tRNA pseudouridylate synthase |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, E (B, A) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A: 1 - 309 (UniProt: Q9WZW0)
| PDB | External Database | Details |
|---|---|---|
| Phe 67 | Tyr 67 | engineered mutation |
| Gln 296 | Asn 296 | see remark 999 |
| Gln 307 | Asn 307 | see remark 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41939.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 42004.5 |
