2AB4

Dissecting the Roles of a Strictly Conserved Tyrosine in Substrate Recognition and Catalysis by Pseudouridine 55 Synthase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001522	biological_process	pseudouridine synthesis
A	0003723	molecular_function	RNA binding
A	0006396	biological_process	RNA processing
A	0006400	biological_process	tRNA modification
A	0008033	biological_process	tRNA processing
A	0009451	biological_process	RNA modification
A	0009982	molecular_function	pseudouridine synthase activity
A	0016853	molecular_function	isomerase activity
A	0031119	biological_process	tRNA pseudouridine synthesis
A	0140098	molecular_function	catalytic activity, acting on RNA
A	0160148	molecular_function	tRNA pseudouridine(55) synthase activity
A	1990481	biological_process	mRNA pseudouridine synthesis

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 310

Chain	Residue
A	TYR9
A	CYS43

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_01080

Chain	Residue	Details
A	ASP39

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1ze1

Chain	Residue	Details
A	ASP39
A	PHE67

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site_id	MCSA1
Number of Residues	4
Details	M-CSA 56

Chain

Residue

Details

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