2AAW
Studies on ligand binding and enzyme inhibition of Plasmodium falciparum glutathione S-transferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | glutathione s-transferase | polymer | 222 | 26091.4 | 2 | GenBank (16518972) Pfam (PF02798) Pfam (PF14497) UniProt (by SIFTS) (Q8ILQ7) | Plasmodium falciparum (malaria parasite P. falciparum) | |
| 2 | C, E (A, C) | S-HEXYLGLUTATHIONE | non-polymer | 392.5 | 2 | Chemie (GTX) | |||
| 3 | D, F (A, C) | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL | non-polymer | 326.4 | 2 | Chemie (P33) | |||
| 4 | G (C) | L-TREITOL | non-polymer | 122.1 | 1 | Chemie (DTL) | |||
| 5 | H, I (A, C) | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A, C: 2 - 211 (GenBank: 16518972)
| PDB | External Database | Details |
|---|---|---|
| Arg -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52182.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1559.9 | |
| All* | Total formula weight | 53742.6 |
