2A7R

Crystal structure of human Guanosine Monophosphate reductase 2 (GMPR2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	GMP reductase 2	polymer	366	39904.6	4	UniProt (Q9P2T1) Pfam (PF00478)	Homo sapiens (human)	Guanosine 5'-monophosphate oxidoreductase 2, Guanosine monophosphate reductase 2
2	E, F, H, I, K... (A, B, C, D)	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
3	G, J, M (A, B, C)	GUANOSINE-5'-MONOPHOSPHATE	non-polymer		363.2	3	Chemie (5GP)
4	P, Q, R, S (A, B, C, D)	water	water		18.0	12	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 348 (UniProt: Q9P2T1)

PDB	External Database	Details
Met -17	-	expression tag
Arg -16	-	expression tag
Gly -15	-	expression tag
Ser -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
Ala -5	-	expression tag
Cys -4	-	expression tag
Glu -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Thr 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	159618.2
Non-Polymers*	Number of molecules	11
	Total formula weight	1858.2
All*	Total formula weight	161476.4

*Water molecules are not included.