2A5T

Crystal Structure Of The NR1/NR2A ligand-binding cores complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	N-methyl-D-aspartate receptor NMDAR1-4a subunit	polymer	292	33340.0	1	UniProt (P35439) GenBank (475566) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Norway rat)	NMDA receptor NR1 subunit
2	B (B)	N-methyl-D-aspartate receptor NMDAR2A subunit	polymer	284	31852.4	1	UniProt (Q00959) GenBank (2155310) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Norway rat)	NMDA receptor NR2A subunit; NMDA receptor NMDAR2A subunit; glutamate receptor, ionotropic, N-methyl D-aspartate 2A
3	C (A)	GLYCINE	non-polymer		75.1	1	Chemie (GLY)
4	D (B)	GLUTAMIC ACID	non-polymer		147.1	1	Chemie (GLU)
5	E, F (A, B)	water	water		18.0	342	Chemie (HOH)

Sequence modifications

A: 2 - 152 (UniProt: P35439)

PDB	External Database	Details
Gly 1	-	SEE REMARK 999
Asn 129	Tyr 529	conflict
Gly 153	-	SEE REMARK 999
Thr 154	-	SEE REMARK 999

A: 155 - 292 (GenBank: 475566)
B: 4 - 142 (UniProt: Q00959)

PDB	External Database	Details
Gly 3	-	SEE REMARK 999
Gly 143	-	SEE REMARK 999
Thr 144	-	SEE REMARK 999

B: 145 - 286 (GenBank: 2155310)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65192.4
Non-Polymers*	Number of molecules	2
	Total formula weight	222.2
All*	Total formula weight	65414.6

*Water molecules are not included.