2A45
Crystal structure of the complex between thrombin and the central "E" region of fibrin
Replaces: 1QVHEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, D) | Thrombin light chain | polymer | 36 | 4096.5 | 2 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | Coagulation factor II |
| 2 | B, D (B, E) | Thrombin heavy chain | polymer | 259 | 29780.2 | 2 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | Coagulation factor II |
| 3 | E, H (G, J) | Fibrinogen alpha chain | polymer | 57 | 6642.4 | 2 | UniProt (P02671) Pfam (PF08702) | Homo sapiens (human) | |
| 4 | F, I (H, K) | Fibrinogen beta chain | polymer | 91 | 9787.1 | 2 | UniProt (P02675) Pfam (PF08702) | Homo sapiens (human) | |
| 5 | G, J (I, L) | Fibrinogen gamma chain | polymer | 45 | 5103.7 | 2 | UniProt (P02679) | Homo sapiens (human) | |
| 6 | K, M (B, E) | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 2 | BIRD (PRD_000020) Chemie (0G6) | PRO2061 | ||
| 7 | L, N (B, E) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 110819.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1097.9 | |
| All* | Total formula weight | 111917.7 |
